Dashboard: Mr. Daniel Crane's Health Overview

Welcome to your personalized health dashboard, Mr. Crane. This section provides a quick summary of the most significant findings from your recent health assessments. The goal is to highlight key areas that require attention and provide a launchpad for exploring your detailed results and action plan.

Total Cholesterol

5.5 mmol/L

Elevated (Ref: <5.2)

LDL Cholesterol

3.45 mmol/L

Elevated (Ref: <2.60)

Homocysteine

16 umol/L

Elevated (Ref: <15)

HbA1c

4.6%

Normal (Ref: <5.7%)

Vitamin D

102 nmol/L

Sufficient (Ref: 74-250)

Hepatitis B Immunity

0 IU/L

No Immunity

Key Takeaways & Focus Areas:

Your recent health screening highlights a few key areas for proactive management, Mr. Crane:

  • Cardiovascular Health: Elevated total cholesterol, LDL cholesterol, and serum homocysteine levels indicate an increased cardiovascular risk. These will be primary targets for your action plan.
  • Genetic Influence: Your DNA analysis reveals an MTRR A66G (+/+) variant, strongly predisposing you to elevated homocysteine. This finding is consistent with your clinical results and guides specific nutritional support.
  • Preventative Care: You currently lack immunity to Hepatitis B. Vaccination is recommended.
  • Strengths: On a positive note, your blood sugar control (HbA1c), inflammatory markers (hsCRP), Vitamin D levels, and organ functions are all within healthy ranges.

This interactive report will guide you through understanding these points in more detail and provide actionable steps. Please explore the sections using the navigation menu.

Clinical Profile

This section presents the detailed findings from your health screening on 24/05/25. Understanding these clinical markers is essential for assessing your current health status and identifying areas for improvement. Interactive charts are provided for key indicators, and a comprehensive table lists all results.

Key Clinical Markers Summary

Marker Your Result Reference Range Status & Brief Note

Notable Observations from Clinical Report:

  • Primary concerns: Elevated lipid markers (Total Cholesterol, LDL-C, Non-HDL-C) and significantly elevated serum homocysteine.
  • Positive findings: Good long-term blood sugar control, low systemic inflammation (hsCRP, ESR), sufficient Vitamin D, normal testosterone and thyroid hormones, good liver and kidney function.
  • Preventative needs: Lack of immunity to Hepatitis B and Hepatitis A.
  • Data Gaps: The report lacks details on current medications, supplements, and specific lifestyle factors (diet, exercise, sleep, stress), which are important for a complete picture.

Genetic Blueprint

Here we explore insights from your Methylation Pathway Analysis (DNA report dated 10/22/2015). Genetic predispositions can offer valuable clues for personalizing your health strategy. Remember, genes are not destiny but can highlight areas needing more attention or specific support. Click on each gene card for more details.

Impact on Key Biological Pathways:

Methylation & Homocysteine:

Your MTRR A66G (+/+) variant is a key factor here, strongly linked to higher homocysteine. AHCY variants (+/-) may also play a role by affecting SAH balance.

Simplified Pathway: Homocysteine --(MTR enzyme, requires B12, supported by MTRR)--> Methionine. Your MTRR +/+ may slow this step.

Transsulfuration (CBS):

Your CBS A360A (+/-) is described as an "open gate", potentially increasing homocysteine processing via this pathway, but may also increase ammonia/sulfite byproducts.

Simplified Pathway: Homocysteine --(CBS enzyme, requires B6)--> Cysteine, Taurine, Glutathione. Your CBS +/- may enhance this flow.

Neurotransmitter Balance:

MAO A +/+ may lead to faster serotonin breakdown. COMT -/- suggests slower dopamine breakdown. This combination has implications for mood and stress response.

Integrated Health Analysis

This crucial section connects the dots between your clinical results and your genetic makeup. Understanding these links provides a more holistic view of your health and guides the personalized recommendations. Expand each topic to learn more.

Personalized Action Plan

Based on your integrated health profile, here is a personalized action plan. It's categorized for clarity. Crucially, all recommendations, especially regarding supplements, MUST be discussed with your healthcare provider, Dr. Amarpreet Kaur, before implementation.

Important Considerations & Disclaimer

Please review these important considerations regarding this report and the necessary next steps with your healthcare provider.

Key Discussion Points for Dr. Amarpreet Kaur:

  • Review this integrated report, especially elevated homocysteine, dyslipidemia, and relevant genetic variants (MTRR, AHCY, CBS, MAO A).
  • Develop a personalized supplementation plan (B12 forms, folate, B6, Omega-3s, Magnesium, Vitamin D, potentially 5-HTP with caution). Critically evaluate supplements from the 2015 DNA report.
  • Confirm Hepatitis B & A vaccination strategy.
  • Refine dietary and lifestyle modifications.
  • Establish follow-up testing schedule (homocysteine, lipids, etc.).
  • Discuss any current symptoms (mood, stress, energy, digestion).

Limitations of This Report:

  • Based only on provided PDFs; lacks broader medical/family history and detailed current lifestyle/medication info.
  • DNA analysis is from 2015; gene expression can change.
  • No direct clinical assessment involved.